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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55c947b6227b6b3a095bebe09b3dcd06c485725ca33f8d3365df9317c5246ba8' 
  AND token = '1Sl0ct6RK8A6gOjc6HA9VT1YRM0ZTvKrv9hJYLpdeFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}