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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2892de8c93051b66cdcf0faba5b6df2b9dd30e3733a3af6000bc71080a32f014' 
  AND token = '17+19epXWu/YcBXsh+FSSdbfCYfX+3fP0l6CE8qa9Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}