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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b7dcab0cda49dc33444fb1f3d0775dc7ce567351aab67f82b49ebaf00078dc' 
  AND token = 'YIb+0jjIMR0B/Vvn/nQ+59tdyxl45XJD68Wi5cmOLTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}