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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea6f683b4dddad005fb2986b011fd1a7819236bd0e3830f1d3d1a387341ebd9a' 
  AND token = 'A6ixxYfbLAkq2EkMartz4XM8CKsn0ANXfWs3ZhgeWsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}