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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddac683543f9aa81bc7be6fd1d6864afeb52f9c31157ba296504aa593dd116f' 
  AND token = 'hV3/KKK3c3ETlmrejtdS5junPhqY1gHmCs4LNDEfaLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}