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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed14c38862fab86afb250d68d420e069f6f78d2a2c88694eb3d403ef640aa082' 
  AND token = 'syfjjrfT2Yx4feXt0pHmgffCgEmcq8v8Ur0dPMRcrgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}