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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153cf02498c6bc5aaae97b056fd72d4a22714a3a9bd86549835f4b8c293184b4' 
  AND token = '87qfQ8S0Vy2wdufnMQMYFETPLzPBMl/n6WcRqwkTtlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}