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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c261655e96788aa3c578258c07e275d96eaf49bb8c5c4678469b82d4bd95e44' 
  AND token = 'IRwIQzX7o+3FGFUatstVBIgcyzAJPxL3l5iObJA+2sY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}