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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2763648645f7332d25c1c1400debdc66e9dbfd4ab839f743f44139d51423f323' 
  AND token = 'ww3Aupcfl5ADuXaenwTMJ4AJL1tEOuGzE8T6NHroLH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}