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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2658cc5d5acb090f5c966d64e796c69aed4647d5758e8835feba77c57a798a' 
  AND token = 'iN2W1FK5F3NMcXA5fHW0VWBSoPQYgh+hp/9cBEFyqFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}