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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc4070ce38a6c15e2437d3930f62581fbdcd7c860b22cbf700bfb04b70d1b05' 
  AND token = '45NytGDWTDW+EbHuk0k9+QwxQvBM33I3kcvmYb+r8AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}