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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1313ded0a5dd6e4688794a148f2ecf0eb3cbea89401ce43f11528cca422bb92' 
  AND token = '0M9Z4a+/MvyY8dvdvDrsNGhD1iylYDrG1XHYcp9rwsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}