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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f979c1e5104f62e42f911c908149ca5802f5720760d7af211972d76e59f1e5df' 
  AND token = 'KHuo2/Q+Q298qEcsNP8bM3XLTHXbZrC2fp4PmXEOcZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}