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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd7060984984826634a6671e652b1f6fa4918224d3ab071d9af64e7816fb3a17' 
  AND token = 'Kwzyh1Nc9YXiRJr9nL/4HL8rQTE6RrpERRia0p1Zhtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}