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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '169385d3825dbdcef2dd96daf993ac0376c06911f838b2474e466b91489ac124' 
  AND token = 'eJApkK7QV52Lbjd4EMbn6+X94pF1TFXepyXd3RDpK9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}