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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2445796a493cb6abb33eb2300fc9abb11651d935ac62a40c03d5091ceb3bfd13' 
  AND token = 'CkyncJ/Fvu/j8HYDUFT9P0a9Q2OF9d3YuSmiJuZ4eOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}