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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc2a60a2e536705a2364199f9cda4ed300516e53aaa0536bced725278c9d0cad' 
  AND token = 'PD8zykkwN/Mm65P6r8aTNXX+zPcOOFCUES3AfLED6mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}