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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afdf35400f18f696baeb0e559187eb0d6f988f40df7c4dd77df8ef5c0cfed45d' 
  AND token = 'gsxh4PwZlPXmOnQeJVqxyYCFgSZklzgw7449VwU7W3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}