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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8fa6c52938ebe8077d39bb143bb0172bad8b3c44543500a34313d78ebaae40' 
  AND token = 'uwwN7O9dz5Ok9WhgC61FOjqakxXFd5MPVkmwgQeiB6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}