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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3e3f9bf4c6931a5b3eefc466ec526ee184c64ffb9311d586ec4172fb520263' 
  AND token = '8icU3sv0+LxcyCOhiXu/0Nu9krvtrY+GEL8ePzhoaag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}