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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880d06fbf0a3889025449b0052ed3aef8ab816c497d71877b0dba2ca1cf58a85' 
  AND token = '2gCqmlyB/knzZT31Ny8hmiIdCy96qg4OFWqcsLPzbzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}