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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a08622fd4364d0d2bc81e51501b81a529d3a0545ce03f237b25ae7f130aa3655' 
  AND token = 'vwwexDqxymWVJUq59x2+dgjac0v6U4UmBAOo/51wzMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}