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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2445dc94f6b30242ed8849540133aa2122aecc0b1b3a0e4677d07cb61d4bfc54' 
  AND token = '2qM6nf/KrIdFZdNh+w5Q3eDh8ATkRqs+WV1fP8CDxj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}