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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b7bc267b00bf4addb99f313491474f230ae6aa694a0cc9235de52416cbcc42' 
  AND token = 'TKs/o9YgxxQtQWX8K7rhyBUnGMA4ljzjpBt2ymt4DDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}