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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1ece1e7acaa135a54bc0bed4a3f20c79434f82500999db2d5dc65e3fec7b6d1' 
  AND token = 'tuWz8dJX8AmLnN6lcfwO+FnXVpDDo5MqOJD6Ixm9P40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}