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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d489ee7bac81fd0ec636990c5610f936d43ea291b5f1828e7929cd077320e7' 
  AND token = 'pd6FJ5qhP82orFwz4YBU5nzOA47yt71Fqmdyq4vnAsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}