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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8319d0b8b2703c89272801fff25647025646c91f89bbca07a5a7990624c266b7' 
  AND token = 'A1xYvWw1A1U01QQBwsJe+H6u8/JnTAm7yYUO8WOsrjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}