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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddab9754c2f84eda45d126c1c0852d907226cd876d18dc578d8d2b1af15dadf3' 
  AND token = '+QbomLUn2pPGTQztzEQUR8kEc7aXhhHFwzkQmX8txCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}