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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427663aebb35a6cef0e4046f449948e688ea6ea997fef7793eae0fcb1fb2f314' 
  AND token = 'ojpDuein1iYi1f/C9oKdV1O3/rQt3dJE+xI75BGLO10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}