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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2123f7733f9e7205acf5a7e6f12f6db5615235318a8918bb204fd47679cd12c' 
  AND token = 'GAp/RxLlv0/F1ttQQ69pjP5H2qqQFWWtNhz9he2Wh5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}