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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '042cf8a88c76a213edbd2c880ebb460fb4f60af0d1fb329aa4b2711289f973c7' 
  AND token = '+e96Sj89MWInJbkBgRfzRQ1DYQJyq+wr1XJVuxUepok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}