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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a22e48b7c79d657f2d75e3d0187c8749431ffa1bac977a162c1661045d9c34' 
  AND token = '69zXQlNe5KS1Ail2h3rPia0EQwT0VVFiBwS7b5Hx+A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}