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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10bead6b69101438bb143a0db9839d00f28095fdf66697521554c8f2f4692e8a' 
  AND token = 'QB2M1n3Q0Hl6y8bYrJaLfQv5WXMHjnnbsCx9tI13MI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}