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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ca18a7c24bd4f0b8389dde255eab6d6704db3e975d693c1e6678bbe0947382' 
  AND token = 'u21i3XeRQcHGemH92lMvKwG6dhN8ttjdU8XrtDP4xmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}