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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4a8f2820b72f6fd711b857a44d8ed83ec999f297e6a8244d465d2f438c50b0' 
  AND token = 'gH6UVGR+5HnLilQpDUGb9AmAekomhBHnUDbn8Or9FJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}