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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5410af1056646e5763ac6f70a1017fa4663fb21da1f78eea7a6130eed99a50d4' 
  AND token = '4B03twf0JK+ThLPSI4h0ThYccfBfE6s9TLZIhfqwimc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}