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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be5e30f931b8ba1e326c3be8511ac718a0e70e886524c9e29d5b94c22e7ebf8a' 
  AND token = 'OQh0EsqTKVd12eoSZs75AXdmVGeRdORqnNzl3SGPVnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}