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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f48cf2f90c9810fc31f7590186f97d1f38b079e524cbf0245bd49bd1c0f8af' 
  AND token = 'zDodfWiMLguHJY5i3S3TOPhoT8qnwt05CwgnAf/S3FA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}