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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42419f7e36d73ea681db438377da21afa88ca74af905598eb409357515f16ea8' 
  AND token = 'ZjmiswjVH9wA5QhDqx51FuwGOyNGcHAXXRZbEDNIT68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}