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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a15b5bfb7fcf52d4aa969ac1271aca6cd345091705b45b0dff850481be0f3e3' 
  AND token = 'o7TgEWXZ2fdvpCoKV92IDGribq2JVFS4FJUBC2iyHVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}