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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303a26cbce2a5aeac5d6a11fe55ac2caf0d02fb09d29547a5e65716cc1651c95' 
  AND token = 'hx5NMnoW5w7lIQL2IDGiFka9jJQ2SyOOc3QJTAKYGmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}