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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f75519f7a57d19a5ceb31b53f497b419afdd78f7f9921d31df2fb810d8ccf49' 
  AND token = 'S4WCZMArf9vGTaP3wQeOcgJoFnIEghwZ00/8G3n3rcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}