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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f442ebf28d2a844cb39ee1246ebfd2ba3fb0b4d057c5eaa81f047c5307069f36' 
  AND token = '1f8AeqaXSo2G1V9+Y/uPL+kUbmYX63V7lLCj6IZVYbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}