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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a36db70010cd3739f5511e54dfc7776ffa298c969556ddf1684aa7a003bc2b3' 
  AND token = '72Z2UCaLuSHfpDjK7pKhWWMeDYL+5uKD9/dDNy8jmPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}