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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd178fa301c8832a53ce96d24d40b2a197ab05cb0bffb4a98249cd2da53072987' 
  AND token = 'w2VjzrXEFZfNBhAywimdF+aT39uFCxM8Jv7Js1CDR44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}