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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '701cef2b581972d39fadfd14e34a4414df8564906e17d5d285e8616a1f8a8a5f' 
  AND token = '/f7q71iNHm9X16yyilbCg+i0PZYm+UPqB1USqm2l5Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}