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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cedcb069dd51bc84b988aaaf3254452c6d1c0c4663e5ce230990e5a66ae60b1' 
  AND token = 'PcF8vkXw+ndMLwbsBm/fmN5v8OF9iEJ+Jjz8LkdAIok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}