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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c173881bba1aad9f5c4fd81eaa87b67743f5e7154376f8d65cdc180625235bd' 
  AND token = '6itab8G43I/RSrCu77WYoSDSsIzN4XhnhHbA63ART2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}