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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc035b0ece78d672b9c664841b97893ff1367ac3efaf3e03d5d1911bae43f391' 
  AND token = 'XH+6TmO3x7tZWhA22xy14H5bceRaEvNtlpY0UfVRIPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}