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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c449f128ce306b5ebd4784582bb705d3b8e10a6ab4fa3936890b74c8b2fae23f' 
  AND token = '6aL17ReCxgm1z/sdfDoBlhX7h7TCBdhrHuK8EVIXEMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}